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Measuring semantic similarities by combining gene ontology annotations and gene co-function networks

BACKGROUND: Gene Ontology (GO) has been used widely to study functional relationships between genes. The current semantic similarity measures rely only on GO annotations and GO structure. This limits the power of GO-based similarity because of the limited proportion of genes that are annotated to GO...

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Detalles Bibliográficos
Autores principales: Peng, Jiajie, Uygun, Sahra, Kim, Taehyong, Wang, Yadong, Rhee, Seung Y, Chen, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339680/
https://www.ncbi.nlm.nih.gov/pubmed/25886899
http://dx.doi.org/10.1186/s12859-015-0474-7