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Effective alignment of RNA pseudoknot structures using partition function posterior log-odds scores

BACKGROUND: RNA pseudoknots play important roles in many biological processes. Previous methods for comparative pseudoknot analysis mainly focus on simultaneous folding and alignment of RNA sequences. Little work has been done to align two known RNA secondary structures with pseudoknots taking into...

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Detalles Bibliográficos
Autores principales: Song, Yang, Hua, Lei, Shapiro, Bruce A, Wang, Jason TL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339682/
https://www.ncbi.nlm.nih.gov/pubmed/25727492
http://dx.doi.org/10.1186/s12859-015-0464-9