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A Comparative Evaluation of a Novel Vaccine in APP/PS1 Mouse Models of Alzheimer's Disease

Immunization against amyloid-beta-peptide (Aβ) has been widely investigated as a potential immunotherapeutic approach for Alzheimer's disease (AD). With the aim of developing an active immunogenic vaccine without need of coadjuvant modification for human trials and therefore avoiding such side...

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Detalles Bibliográficos
Autores principales: Carrera, Iván, Etcheverría, Ignacio, Fernández-Novoa, Lucía, Lombardi, Valter Ruggero Maria, Lakshmana, Madepalli Krishnappa, Cacabelos, Ramón, Vigo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339718/
https://www.ncbi.nlm.nih.gov/pubmed/25759822
http://dx.doi.org/10.1155/2015/807146