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A systematic evaluation of high-dimensional, ensemble-based regression for exploring large model spaces in microbiome analyses

BACKGROUND: Microbiome studies incorporate next-generation sequencing to obtain profiles of microbial communities. Data generated from these experiments are high-dimensional with a rich correlation structure but modest sample sizes. A statistical model that utilizes these microbiome profiles to expl...

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Detalles Bibliográficos
Autores principales: Shankar, Jyoti, Szpakowski, Sebastian, Solis, Norma V, Mounaud, Stephanie, Liu, Hong, Losada, Liliana, Nierman, William C, Filler, Scott G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339743/
https://www.ncbi.nlm.nih.gov/pubmed/25638274
http://dx.doi.org/10.1186/s12859-015-0467-6