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A systematic evaluation of high-dimensional, ensemble-based regression for exploring large model spaces in microbiome analyses
BACKGROUND: Microbiome studies incorporate next-generation sequencing to obtain profiles of microbial communities. Data generated from these experiments are high-dimensional with a rich correlation structure but modest sample sizes. A statistical model that utilizes these microbiome profiles to expl...
Autores principales: | Shankar, Jyoti, Szpakowski, Sebastian, Solis, Norma V, Mounaud, Stephanie, Liu, Hong, Losada, Liliana, Nierman, William C, Filler, Scott G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339743/ https://www.ncbi.nlm.nih.gov/pubmed/25638274 http://dx.doi.org/10.1186/s12859-015-0467-6 |
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