The effect of rare variants on inflation of the test statistics in case–control analyses

BACKGROUND: The detection of bias due to cryptic population structure is an important step in the evaluation of findings of genetic association studies. The standard method of measuring this bias in a genetic association study is to compare the observed median association test statistic to the expec...

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Detalles Bibliográficos
Autores principales: Pirie, Ailith, Wood, Angela, Lush, Michael, Tyrer, Jonathan, Pharoah, Paul DP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339749/
https://www.ncbi.nlm.nih.gov/pubmed/25888290
http://dx.doi.org/10.1186/s12859-015-0496-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339749/
https://www.ncbi.nlm.nih.gov/pubmed/25888290
http://dx.doi.org/10.1186/s12859-015-0496-1

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