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The effect of rare variants on inflation of the test statistics in case–control analyses
BACKGROUND: The detection of bias due to cryptic population structure is an important step in the evaluation of findings of genetic association studies. The standard method of measuring this bias in a genetic association study is to compare the observed median association test statistic to the expec...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339749/ https://www.ncbi.nlm.nih.gov/pubmed/25888290 http://dx.doi.org/10.1186/s12859-015-0496-1 |