Recognition and Sensing of Low-Epitope Targets via Ternary Complexes with Oligonucleotides and Synthetic Receptors

Oligonucleotide-based receptors or aptamers can interact with small molecules, but the ability to achieve high-affinity and selectivity of these interactions depends strongly on functional groups or epitopes displayed by the binding targets. Some classes of targets are particularly challenging: for...

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Detalles Bibliográficos
Autores principales: Yang, Kyung-Ae, Barbu, Michaela, Halim, Marlin, Pallavi, Payal, Kim, Benjamin, Kolpashchikov, Dmitry, Pecic, Stevan, Taylor, Steven, Worgall, Tilla S., Stojanovic, Milan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339820/
https://www.ncbi.nlm.nih.gov/pubmed/25343606
http://dx.doi.org/10.1038/nchem.2058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339820/
https://www.ncbi.nlm.nih.gov/pubmed/25343606
http://dx.doi.org/10.1038/nchem.2058

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