Retrotransposition of Long Interspersed Nucleotide Element-1 Is Associated with Colitis but Not Tumors in a Murine Colitic Cancer Model

Long interspersed element-1 (L1) is a transposable element that can move within the genome, potentially leading to genome diversity and modified gene function. Although L1 activity in somatic cells is normally suppressed through DNA methylation, some L1s are activated in tumors including colorectal...

Descripción completa

Detalles Bibliográficos
Autores principales: Otsubo, Takeshi, Okamura, Tadashi, Hagiwara, Teruki, Ishizaka, Yukihito, Dohi, Taeko, Kawamura, Yuki I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339839/
https://www.ncbi.nlm.nih.gov/pubmed/25710700
http://dx.doi.org/10.1371/journal.pone.0116072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339839/
https://www.ncbi.nlm.nih.gov/pubmed/25710700
http://dx.doi.org/10.1371/journal.pone.0116072

Ejemplares similares