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Control of cytoplasmic dynein force production and processivity by its C-terminal domain

Cytoplasmic dynein is a microtubule motor involved in cargo transport, nuclear migration and cell division. Despite structural conservation of the dynein motor domain from yeast to higher eukaryotes, the extensively studied S. cerevisiae dynein behaves distinctly from mammalian dyneins, which produc...

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Detalles Bibliográficos
Autores principales: Nicholas, Matthew P., Höök, Peter, Brenner, Sibylle, Wynne, Caitlin L., Vallee, Richard B., Gennerich, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339881/
https://www.ncbi.nlm.nih.gov/pubmed/25670086
http://dx.doi.org/10.1038/ncomms7206