Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity

To cause food-borne botulism, botulinum neurotoxin (BoNT) in the gastrointestinal lumen must traverse the intestinal epithelial barrier. However, the mechanism by which BoNT crosses the intestinal epithelial barrier remains unclear. BoNTs are produced along with one or more non-toxic components, wit...

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Detalles Bibliográficos
Autores principales: Matsumura, Takuhiro, Sugawara, Yo, Yutani, Masahiro, Amatsu, Sho, Yagita, Hideo, Kohda, Tomoko, Fukuoka, Shin-Ichi, Nakamura, Yutaka, Fukuda, Shinji, Hase, Koji, Ohno, Hiroshi, Fujinaga, Yukako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339894/
https://www.ncbi.nlm.nih.gov/pubmed/25687350
http://dx.doi.org/10.1038/ncomms7255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339894/
https://www.ncbi.nlm.nih.gov/pubmed/25687350
http://dx.doi.org/10.1038/ncomms7255

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