A Comparison of Methods for Treatment Selection in Seamless Phase II/III Clinical Trials Incorporating Information on Short-Term Endpoints

In an adaptive seamless phase II/III clinical trial interim analysis, data are used for treatment selection, enabling resources to be focused on comparison of more effective treatment(s) with a control. In this paper, we compare two methods recently proposed to enable use of short-term endpoint data...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunz, Cornelia Ursula, Friede, Tim, Parsons, Nicholas, Todd, Susan, Stallard, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339952/
https://www.ncbi.nlm.nih.gov/pubmed/24697322
http://dx.doi.org/10.1080/10543406.2013.840646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339952/
https://www.ncbi.nlm.nih.gov/pubmed/24697322
http://dx.doi.org/10.1080/10543406.2013.840646

Ejemplares similares