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A Comparison of Methods for Treatment Selection in Seamless Phase II/III Clinical Trials Incorporating Information on Short-Term Endpoints
In an adaptive seamless phase II/III clinical trial interim analysis, data are used for treatment selection, enabling resources to be focused on comparison of more effective treatment(s) with a control. In this paper, we compare two methods recently proposed to enable use of short-term endpoint data...
Autores principales: | Kunz, Cornelia Ursula, Friede, Tim, Parsons, Nicholas, Todd, Susan, Stallard, Nigel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339952/ https://www.ncbi.nlm.nih.gov/pubmed/24697322 http://dx.doi.org/10.1080/10543406.2013.840646 |
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