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Development and Validation of a Liquid Chromatography-Mass Spectrometry Method for the Determination of Zileuton in Human Plasma

A selective and sensitive liquid chromatography-tandem mass spectrometric method (LC-MS/MS) has been developed and validated for the quantification of zileuton in human plasma. Deuterated internal standard (zileuton D4) was used as the internal standard (ISTD). Zileuton was extracted by liquid-liqui...

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Detalles Bibliográficos
Autores principales: Prakash, Katakam, Adiki, Shanta K, Kalakuntla, Rama Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientia Pharmaceutica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339974/
https://www.ncbi.nlm.nih.gov/pubmed/25853069
http://dx.doi.org/10.3797/scipharm.1402-19