Engrailed 1 Mediates Correct Formation of Limb Innervation through Two Distinct Mechanisms

Engrailed-1 (En1) is expressed in the ventral ectoderm of the developing limb where it plays an instructive role in the dorsal-ventral patterning of the forelimb. Besides its well-described role as a transcription factor in regulating gene expression through its DNA-binding domain, En1 may also be s...

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Detalles Bibliográficos
Autores principales: Huettl, Rosa-Eva, Luxenhofer, Georg, Bianchi, Elisa, Haupt, Corinna, Joshi, Rajiv, Prochiantz, Alain, Huber, Andrea B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340014/
https://www.ncbi.nlm.nih.gov/pubmed/25710467
http://dx.doi.org/10.1371/journal.pone.0118505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340014/
https://www.ncbi.nlm.nih.gov/pubmed/25710467
http://dx.doi.org/10.1371/journal.pone.0118505

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