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Involvement of sigma-1 receptor in astrocyte activation induced by methamphetamine via up-regulation of its own expression
BACKGROUND: Although it has been documented that methamphetamine induces astrocyte activation, the mechanism(s) underlying this effect remain poorly understood. We thus sought to examine the molecular mechanisms involved in methamphetamine-mediated activation of astrocytes with a focus on the role o...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340104/ https://www.ncbi.nlm.nih.gov/pubmed/25889537 http://dx.doi.org/10.1186/s12974-015-0250-7 |