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Involvement of sigma-1 receptor in astrocyte activation induced by methamphetamine via up-regulation of its own expression

BACKGROUND: Although it has been documented that methamphetamine induces astrocyte activation, the mechanism(s) underlying this effect remain poorly understood. We thus sought to examine the molecular mechanisms involved in methamphetamine-mediated activation of astrocytes with a focus on the role o...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Lv, Xuan, Bai, Ying, Zhu, Xinjian, Wu, Xiaodong, Chao, Jie, Duan, Ming, Buch, Shilpa, Chen, Ling, Yao, Honghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340104/
https://www.ncbi.nlm.nih.gov/pubmed/25889537
http://dx.doi.org/10.1186/s12974-015-0250-7