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Nuclear receptor subfamily 4, group A, member 1 inhibits extrinsic apoptosis and reduces caspase-8 activity in H(2)O(2)-induced human HUC-F2 fibroblasts

Objective: Apoptosis is characterized by distinct morphological and biochemical changes that occur upon activation of a family of serine proteases known as caspases. Reactive oxygen species (ROS) induce apoptosis in many cell systems. Nuclear receptor subfamily 4, group A, member 1 (NR4A1) has been...

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Detalles Bibliográficos
Autores principales: Shimizu, Yuri, Miyakura, Reiko, Otsuka, Yuzuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340241/
https://www.ncbi.nlm.nih.gov/pubmed/25330024
http://dx.doi.org/10.1179/1351000214Y.0000000109