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Nuclear receptor subfamily 4, group A, member 1 inhibits extrinsic apoptosis and reduces caspase-8 activity in H(2)O(2)-induced human HUC-F2 fibroblasts
Objective: Apoptosis is characterized by distinct morphological and biochemical changes that occur upon activation of a family of serine proteases known as caspases. Reactive oxygen species (ROS) induce apoptosis in many cell systems. Nuclear receptor subfamily 4, group A, member 1 (NR4A1) has been...
Autores principales: | Shimizu, Yuri, Miyakura, Reiko, Otsuka, Yuzuru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340241/ https://www.ncbi.nlm.nih.gov/pubmed/25330024 http://dx.doi.org/10.1179/1351000214Y.0000000109 |
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