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High expression of neuroguidin increases the sensitivity of acute myeloid leukemia cells to chemotherapeutic drugs

Neuroguidin (NGDN) is a eukaryotic translation initiation factor 4E binding protein. The purpose of this study was to clarify the function of NGDN and its possible mechanism of action in human myeloid leukemia cells. Proliferation inhibition and apoptosis in NGDN over-expressing myeloid multidrug-re...

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Detalles Bibliográficos
Autores principales: Chen, Kejun, Lü, Shuqing, Cheng, Hui, Tang, Gusheng, Liu, Min, Zhou, Hong, Wang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340276/
https://www.ncbi.nlm.nih.gov/pubmed/25887473
http://dx.doi.org/10.1186/s13045-015-0108-6