Attenuation of acute stroke injury in rat brain by minocycline promotes blood–brain barrier remodeling and alternative microglia/macrophage activation during recovery

BACKGROUND: Minocycline reduces reperfusion injury by inhibiting matrix metalloproteinases (MMPs) and microglia activity after cerebral ischemia. Prior studies of minocycline investigated short-term neuroprotective effects during subacute stage of stroke; however, the late effects of minocycline aga...

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Detalles Bibliográficos
Autores principales: Yang, Yirong, Salayandia, Victor M, Thompson, Jeffrey F, Yang, Lisa Y, Estrada, Eduardo Y, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340283/
https://www.ncbi.nlm.nih.gov/pubmed/25889169
http://dx.doi.org/10.1186/s12974-015-0245-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340283/
https://www.ncbi.nlm.nih.gov/pubmed/25889169
http://dx.doi.org/10.1186/s12974-015-0245-4

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