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Inhibition of CDC25B Phosphatase Through Disruption of Protein–Protein Interaction
[Image: see text] CDC25 phosphatases are key cell cycle regulators and represent very attractive but challenging targets for anticancer drug discovery. Here, we explored whether fragment-based screening represents a valid approach to identify inhibitors of CDC25B. This resulted in identification of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340349/ https://www.ncbi.nlm.nih.gov/pubmed/25423142 http://dx.doi.org/10.1021/cb500883h |