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The role of dolutegravir in the management of HIV infection

Dolutegravir is the most recent integrase strand transfer inhibitor approved for HIV-1 infection in both treatment-naïve and experienced patients. As a tricyclic carbamoyl pyridone analog, dolutegravir is rapidly absorbed and distributes through the cerebrospinal fluid. It is hepatically metabolized...

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Detalles Bibliográficos
Autores principales: Miller, Misty M, Liedtke, Michelle D, Lockhart, Staci M, Rathbun, R Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340460/
https://www.ncbi.nlm.nih.gov/pubmed/25733917
http://dx.doi.org/10.2147/IDR.S58706