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Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies

BACKGROUND: Every year, hundreds of thousands of patients experience treatment failure or adverse drug reactions (ADRs), many of which could be prevented by pharmacogenomic testing. However, the primary knowledge needed for clinical pharmacogenomics is currently dispersed over disparate data structu...

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Detalles Bibliográficos
Autores principales: Samwald, Matthias, Miñarro Giménez, Jose Antonio, Boyce, Richard D, Freimuth, Robert R, Adlassnig, Klaus-Peter, Dumontier, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340468/
https://www.ncbi.nlm.nih.gov/pubmed/25880555
http://dx.doi.org/10.1186/s12911-015-0130-1