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Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies
BACKGROUND: Every year, hundreds of thousands of patients experience treatment failure or adverse drug reactions (ADRs), many of which could be prevented by pharmacogenomic testing. However, the primary knowledge needed for clinical pharmacogenomics is currently dispersed over disparate data structu...
Autores principales: | Samwald, Matthias, Miñarro Giménez, Jose Antonio, Boyce, Richard D, Freimuth, Robert R, Adlassnig, Klaus-Peter, Dumontier, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340468/ https://www.ncbi.nlm.nih.gov/pubmed/25880555 http://dx.doi.org/10.1186/s12911-015-0130-1 |
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