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A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

Most transmembrane proteins are selected as transport vesicle cargo through the recognition of short, linear amino acid motifs in their cytoplasmic portions by vesicle coat proteins. In the case of clathrin-coated vesicles (CCVs) the motifs are recognised by clathrin adaptors. The AP2 adaptor comple...

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Detalles Bibliográficos
Autores principales: Kelly, Bernard T., McCoy, Airlie J., Späte, Kira, Miller, Sharon E., Evans, Philip R., Höning, Stefan, Owen, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340503/
https://www.ncbi.nlm.nih.gov/pubmed/19140243
http://dx.doi.org/10.1038/nature07422