Cargando…

The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens

Chemokine-directed leukocyte migration is a critical component of all innate and adaptive immune responses. The atypical chemokine receptor ACKR2 is expressed by lymphatic endothelial cells and scavenges pro-inflammatory CC chemokines to indirectly subdue leukocyte migration. This contributes to the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hansell, Chris AH, MacLellan, Lindsay M, Oldham, Rachel S, Doonan, James, Chapple, Katie J, Anderson, Elinor JR, Linington, Christopher, McInnes, Iain B, Nibbs, Robert JB, Goodyear, Carl S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340511/
https://www.ncbi.nlm.nih.gov/pubmed/25348934
http://dx.doi.org/10.1038/icb.2014.90