Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration

The recent revolution in age-related macular degeneration (AMD) genetics has demonstrated that genetic alterations affecting the alternative pathway of the complement cascade have a major influence on AMD risk. One of the two most important genetic loci is on chromosome 1 and contains genes encoding...

Descripción completa

Detalles Bibliográficos
Autores principales: Clark, Simon J., Bishop, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340553/
https://www.ncbi.nlm.nih.gov/pubmed/25729613
http://dx.doi.org/10.3390/jcm4010018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340553/
https://www.ncbi.nlm.nih.gov/pubmed/25729613
http://dx.doi.org/10.3390/jcm4010018

Ejemplares similares