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Direct Observation of Distinct A/P Hybrid-State tRNAs in Translocating Ribosomes

Transfer RNAs (tRNAs) link the genetic code in the form of messenger RNA (mRNA) to protein sequence. Translocation of tRNAs through the ribosome from aminoacyl (A) site to peptidyl (P) site and from P site to exit site is catalyzed in eukaryotes by the translocase elongation factor 2 (EF-2) and in p...

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Detalles Bibliográficos
Autores principales: Flanagan, John F., Namy, Olivier, Brierley, Ian, Gilbert, Robert J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340587/
https://www.ncbi.nlm.nih.gov/pubmed/20159470
http://dx.doi.org/10.1016/j.str.2009.12.007