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Transhydrogenase Promotes the Robustness and Evolvability of E. coli Deficient in NADPH Production

Metabolic networks revolve around few metabolites recognized by diverse enzymes and involved in myriad reactions. Though hub metabolites are considered as stepping stones to facilitate the evolutionary expansion of biochemical pathways, changes in their production or consumption often impair cellula...

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Detalles Bibliográficos
Autores principales: Chou, Hsin-Hung, Marx, Christopher J., Sauer, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340650/
https://www.ncbi.nlm.nih.gov/pubmed/25715029
http://dx.doi.org/10.1371/journal.pgen.1005007