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Transhydrogenase Promotes the Robustness and Evolvability of E. coli Deficient in NADPH Production
Metabolic networks revolve around few metabolites recognized by diverse enzymes and involved in myriad reactions. Though hub metabolites are considered as stepping stones to facilitate the evolutionary expansion of biochemical pathways, changes in their production or consumption often impair cellula...
Autores principales: | Chou, Hsin-Hung, Marx, Christopher J., Sauer, Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340650/ https://www.ncbi.nlm.nih.gov/pubmed/25715029 http://dx.doi.org/10.1371/journal.pgen.1005007 |
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