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Cytogenetic significance of chromosome 17 aberrations and P53 gene mutations as prognostic markers in oral squamous cell carcinoma

BACKGROUND: Cytogenetic analysis has detected an accumulation of genetic lesions in oral cancers. Numerical changes in chromosome 17 might be associated with an up-regulation of p53 gene, and could contribute to critical events in carcinogenesis. The aim of this study was to reveal possible correlat...

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Detalles Bibliográficos
Autores principales: Zedan, Walid, Mourad, Mohamed I, El-Aziz, Sherin M Abd, Salamaa, Nagla M, Shalaby, Asem A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340679/
https://www.ncbi.nlm.nih.gov/pubmed/25881131
http://dx.doi.org/10.1186/s13000-015-0232-1