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Neutrophil-derived JAML Inhibits Repair of Intestinal Epithelial Injury During Acute Inflammation
Neutrophil transepithelial migration (TEM) during acute inflammation is associated with mucosal injury. Using models of acute mucosal injury in-vitro and in-vivo, we describe a new mechanism by which neutrophils infiltrating the intestinal mucosa disrupt epithelial homeostasis. We report that juncti...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340686/ https://www.ncbi.nlm.nih.gov/pubmed/24621992 http://dx.doi.org/10.1038/mi.2014.12 |