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Wnt Antagonist Secreted Frizzled-Related Protein 4 Upregulates Adipogenic Differentiation in Human Adipose Tissue-Derived Mesenchymal Stem Cells

With more than 1.4 billion overweight or obese adults worldwide, obesity and progression of the metabolic syndrome are major health and economic challenges. To address mechanisms of obesity, adipose tissue-derived mesenchymal stem cells (ADSCs) are being studied to detail the molecular mechanisms in...

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Detalles Bibliográficos
Autores principales: Visweswaran, Malini, Schiefer, Luca, Arfuso, Frank, Dilley, Rodney J., Newsholme, Philip, Dharmarajan, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340908/
https://www.ncbi.nlm.nih.gov/pubmed/25714610
http://dx.doi.org/10.1371/journal.pone.0118005