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Enhanced Neurite Outgrowth of Human Model (NT2) Neurons by Small-Molecule Inhibitors of Rho/ROCK Signaling

Axonal injury in the adult human central nervous system often results in loss of sensation and motor functions. Promoting regeneration of severed axons requires the inactivation of growth inhibitory influences from the tissue environment and stimulation of the neuron intrinsic growth potential. Espe...

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Detalles Bibliográficos
Autores principales: Roloff, Frank, Scheiblich, Hannah, Dewitz, Carola, Dempewolf, Silke, Stern, Michael, Bicker, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340918/
https://www.ncbi.nlm.nih.gov/pubmed/25714396
http://dx.doi.org/10.1371/journal.pone.0118536