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Proportional Upregulation of CD97 Isoforms in Glioblastoma and Glioblastoma-Derived Brain Tumor Initiating Cells

CD97 is a novel glioma antigen that confers an invasive phenotype and poor survival in patients with glioblastoma (GBM), the most aggressive primary malignant brain tumor. The short isoform of CD97, known as EGF(1,2,5), has been shown to promote invasion and metastasis, but its role in gliomas and G...

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Detalles Bibliográficos
Autores principales: Safaee, Michael, Fakurnejad, Shayan, Bloch, Orin, Clark, Aaron J., Ivan, Michael E., Sun, Matthew Z., Oh, Taemin, Phillips, Joanna J., Parsa, Andrew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340952/
https://www.ncbi.nlm.nih.gov/pubmed/25714433
http://dx.doi.org/10.1371/journal.pone.0111532