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deML: robust demultiplexing of Illumina sequences using a likelihood-based approach

Motivation: Pooling multiple samples increases the efficiency and lowers the cost of DNA sequencing. One approach to multiplexing is to use short DNA indices to uniquely identify each sample. After sequencing, reads must be assigned in silico to the sample of origin, a process referred to as demulti...

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Detalles Bibliográficos
Autores principales: Renaud, Gabriel, Stenzel, Udo, Maricic, Tomislav, Wiebe, Victor, Kelso, Janet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341068/
https://www.ncbi.nlm.nih.gov/pubmed/25359895
http://dx.doi.org/10.1093/bioinformatics/btu719