dPob/EMC is essential for biosynthesis of rhodopsin and other multi-pass membrane proteins in Drosophila photoreceptors

In eukaryotes, most integral membrane proteins are synthesized, integrated into the membrane, and folded properly in the endoplasmic reticulum (ER). We screened the mutants affecting rhabdomeric expression of rhodopsin 1 (Rh1) in the Drosophila photoreceptors and found that dPob/EMC3, EMC1, and EMC8...

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Detalles Bibliográficos
Autores principales: Satoh, Takunori, Ohba, Aya, Liu, Ziguang, Inagaki, Tsuyoshi, Satoh, Akiko K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341237/
https://www.ncbi.nlm.nih.gov/pubmed/25715730
http://dx.doi.org/10.7554/eLife.06306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341237/
https://www.ncbi.nlm.nih.gov/pubmed/25715730
http://dx.doi.org/10.7554/eLife.06306

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