Paroxetine engenders analgesic effects through inhibition of p38 phosphorylation in a rat migraine model☆

In this study, a model of migraine was established by electrical stimulation of the superior sagittal sinus in rats. These rats were then treated orally with paroxetine at doses of 2.5, 5, or 10 mg/kg per day for 14 days. Following treatment, mechanical withdrawal thresholds were significantly highe...

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Detalles Bibliográficos
Autores principales: Wang, Chuanming, Bi, Wei, Liang, Yanran, Jing, Xiuna, Xiao, Songhua, Fang, Yannan, Shi, Qiaoyun, Tao, Enxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Research and Report: Brain Injury and Neural Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341271/
https://www.ncbi.nlm.nih.gov/pubmed/25722689
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.13.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341271/
https://www.ncbi.nlm.nih.gov/pubmed/25722689
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.13.007

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