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Early Life Stress as a Risk Factor for Substance use Disorders: Clinical and Neurobiological Substrates

BACKGROUND: Early Life Stress (ELS) can profoundly influence an individual's genotype and phenotype. Effects of ELS can manifest in the short-term, late life and even in subsequent generations. ELS activate corticotrophin releasing factor (CRF); CRF influences drug seeking and addiction. The ai...

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Detalles Bibliográficos
Autores principales: Varghese, Sajoy Purathumuriyil, Montalvo-Ortiz, Janitza L., Csernansky, John G., Eiger, Rodney I., Herrold, Amy A., Koola, Maju Mathew, Dong, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341308/
https://www.ncbi.nlm.nih.gov/pubmed/25722510
http://dx.doi.org/10.4103/0253-7176.150816