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Early Life Stress as a Risk Factor for Substance use Disorders: Clinical and Neurobiological Substrates
BACKGROUND: Early Life Stress (ELS) can profoundly influence an individual's genotype and phenotype. Effects of ELS can manifest in the short-term, late life and even in subsequent generations. ELS activate corticotrophin releasing factor (CRF); CRF influences drug seeking and addiction. The ai...
Autores principales: | Varghese, Sajoy Purathumuriyil, Montalvo-Ortiz, Janitza L., Csernansky, John G., Eiger, Rodney I., Herrold, Amy A., Koola, Maju Mathew, Dong, Hongxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341308/ https://www.ncbi.nlm.nih.gov/pubmed/25722510 http://dx.doi.org/10.4103/0253-7176.150816 |
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