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Serine 133 phosphorylation is not required for hippocampal CREB-mediated transcription and behavior

The cAMP response element (CRE)-binding protein, CREB, is a transcription factor whose activity in the brain is critical for long-term memory formation. Phosphorylation of Ser133 in the kinase-inducible domain (KID), that in turn leads to the recruitment of the transcriptional coactivator CREB-bindi...

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Detalles Bibliográficos
Autores principales: Briand, Lisa A., Lee, Bridgin G., Lelay, John, Kaestner, Klaus H., Blendy, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341363/
https://www.ncbi.nlm.nih.gov/pubmed/25593297
http://dx.doi.org/10.1101/lm.037044.114