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Serine 133 phosphorylation is not required for hippocampal CREB-mediated transcription and behavior
The cAMP response element (CRE)-binding protein, CREB, is a transcription factor whose activity in the brain is critical for long-term memory formation. Phosphorylation of Ser133 in the kinase-inducible domain (KID), that in turn leads to the recruitment of the transcriptional coactivator CREB-bindi...
Autores principales: | Briand, Lisa A., Lee, Bridgin G., Lelay, John, Kaestner, Klaus H., Blendy, Julie A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341363/ https://www.ncbi.nlm.nih.gov/pubmed/25593297 http://dx.doi.org/10.1101/lm.037044.114 |
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