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Human RNASET2 derivatives as potential anti-angiogenic agents: actin binding sequence identification and characterization

Human RNASET2 (hRNASET2) has been demonstrated to exert antiangiogenic and antitumorigenic effects independent of its ribonuclease capacity. We suggested that RNASET2 exerts its antiangiogenic and antitumorigenic activities via binding to actin and consequently inhibits cell motility. We focused her...

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Detalles Bibliográficos
Autores principales: Nesiel-Nuttman, Liron, Doron, Shani, Schwartz, Betty, Shoseyov, Oded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341462/
https://www.ncbi.nlm.nih.gov/pubmed/25815360