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Simple, rapid and accurate molecular diagnosis of acute promyelocytic leukemia by loop mediated amplification technology

The diagnostic work-up of acute promyelocytic leukemia (APL) includes the cytogenetic demonstration of the t(15;17) translocation and/or the PML-RARA chimeric transcript by RQ-PCR or RT-PCR. This latter assays provide suitable results in 3-6 hours. We describe here two new, rapid and specific assays...

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Detalles Bibliográficos
Autores principales: Spinelli, Orietta, Rambaldi, Alessandro, Rigo, Francesca, Zanghì, Pamela, D'Agostini, Elena, Amicarelli, Giulia, Colotta, Francesco, Divona, Mariadomenica, Ciardi, Claudia, Coco, Francesco Lo, Minnucci, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341464/
https://www.ncbi.nlm.nih.gov/pubmed/25815362