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CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons

Neuropeptides released from dense-core vesicles (DCVs) modulate neuronal activity, but the molecules driving DCV secretion in mammalian neurons are largely unknown. We studied the role of calcium-activator protein for secretion (CAPS) proteins in neuronal DCV secretion at single vesicle resolution....

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Detalles Bibliográficos
Autores principales: Farina, Margherita, van de Bospoort, Rhea, He, Enqi, Persoon, Claudia M, van Weering, Jan RT, Broeke, Jurjen H, Verhage, Matthijs, Toonen, Ruud F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341531/
https://www.ncbi.nlm.nih.gov/pubmed/25719439
http://dx.doi.org/10.7554/eLife.05438