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Identification of essential amino acid residues in the nisin dehydratase NisB

Nisin is a posttranslationally-modified antimicrobial peptide that has the ability to induce its own biosynthesis. Serines and threonines in the modifiable core peptide part of precursor nisin are dehydrated to dehydroalanines and dehydrobutyrines by the dehydratase NisB, and subsequently cysteines...

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Detalles Bibliográficos
Autores principales: Khusainov, Rustem, van Heel, Auke J., Lubelski, Jacek, Moll, Gert N., Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341554/
https://www.ncbi.nlm.nih.gov/pubmed/25767464
http://dx.doi.org/10.3389/fmicb.2015.00102