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Exploration of Aspergillus fumigatus Ras pathways for novel antifungal drug targets

Ras pathway signaling is a critical virulence determinant for pathogenic fungi. Localization of Ras to the plasma membrane (PM) is required for Ras network interactions supporting fungal growth and virulence. For example, loss of Aspergillus fumigatus RasA signaling at the PM via inhibition of palmi...

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Detalles Bibliográficos
Autores principales: Abdallah, Qusai Al, Fortwendel, Jarrod R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341556/
https://www.ncbi.nlm.nih.gov/pubmed/25767465
http://dx.doi.org/10.3389/fmicb.2015.00128