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Exploration of Aspergillus fumigatus Ras pathways for novel antifungal drug targets
Ras pathway signaling is a critical virulence determinant for pathogenic fungi. Localization of Ras to the plasma membrane (PM) is required for Ras network interactions supporting fungal growth and virulence. For example, loss of Aspergillus fumigatus RasA signaling at the PM via inhibition of palmi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341556/ https://www.ncbi.nlm.nih.gov/pubmed/25767465 http://dx.doi.org/10.3389/fmicb.2015.00128 |