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Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?

INTRODUCTION: The aim of this study was to explore the impact of augmented creatinine clearance and differing minimum inhibitory concentrations (MIC) on piperacillin pharmacokinetic/pharmacodynamic (PK/PD) target attainment (time above MIC (fT(>MIC))) in critically ill patients with sepsis receiv...

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Detalles Bibliográficos
Autores principales: Udy, Andrew A, Lipman, Jeffrey, Jarrett, Paul, Klein, Kerenaftali, Wallis, Steven C, Patel, Kashyap, Kirkpatrick, Carl MJ, Kruger, Peter S, Paterson, David L, Roberts, Michael S, Roberts, Jason A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341874/
https://www.ncbi.nlm.nih.gov/pubmed/25632974
http://dx.doi.org/10.1186/s13054-015-0750-y