Filter-free exhaustive odds ratio-based genome-wide interaction approach pinpoints evidence for interaction in the HLA region in psoriasis

BACKGROUND: Deciphering the genetic architecture of complex traits is still a major challenge for human genetics. In most cases, genome-wide association studies have only partially explained the heritability of traits and diseases. Epistasis, one potentially important cause of this missing heritabil...

Descripción completa

Detalles Bibliográficos
Autores principales: Grange, Laura, Bureau, Jean-François, Nikolayeva, Iryna, Paul, Richard, Van Steen, Kristel, Schwikowski, Benno, Sakuntabhai, Anavaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341885/
https://www.ncbi.nlm.nih.gov/pubmed/25655172
http://dx.doi.org/10.1186/s12863-015-0174-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341885/
https://www.ncbi.nlm.nih.gov/pubmed/25655172
http://dx.doi.org/10.1186/s12863-015-0174-3

Ejemplares similares